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所在位置:所有产品 > 抗体抗原 > 一抗 > eNOS/NOS3抗体
eNOS/NOS3抗体图片
产品货号:
Z31258
中文名称:
eNOS/NOS3抗体
英文名称:
Anti-eNOS/NOS3 Antibody (Clone#6H2)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-eNOS/NOS3 Antibody (Clone#6H2)
指标别名cNOS;Constitutive NOS;EC NOS;ECNOS;Endothelial NOS;eNOS;NOS type III;NOS3;NOSIII
克隆性Monoclonal
检验物种human
应用范围IHC,ELISA
基因名称NOS3
克隆号6H2
抗体来源Mouse
抗体类型IgG
免疫原Purified recombinant fragment of human NOS3 expressed in E.Coli.
计算分子量133KD
成分Ascitic fluid containing 0.03% sodium azide.
纯化方式Affinity purification
浓度1mg/mL
产品形态溶液
保存条件-20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。
背景资料NOS3(Nitric Oxide Synthase 3),also called ENOS,a?nitric oxide synthase?that generates?NO?in?blood vessels?and is involved with regulating?vascular tone?by inhibiting?smooth muscle?contraction and platelet?aggregation.The NOS3 gene is mapped on 7q36.1.Variations in this gene are associated with susceptibility to?coronary spasm.?Fulton et al.?(1999) concluded the eNOS is an AKT substrate linking signal transduction by AKT to the release of the gaseous second messenger nitric oxide.?AKT mediates the activation of eNOS,leading to increased nitric oxide production.Inhibition of the PI3K AKT pathway or mutation of the AKT site on eNOS protein at serine-1177 attenuated the serine phosphorylation and prevented the activation of eNOS.RT-PCR analysis showed that expression of?NOS3?in human umbilical vein endothelial cells (HUVECs) and human aortic vascular smooth muscle cells (HAOVSMCs) was inversely proportional to that of NOS3AS.
Uniprot IDP29474
基因名全称Nitric oxide synthase,endothelial
蛋白名全称Nitric oxide synthase,endothelial
推荐稀释比IHC 1:200~1:1000
ELISA 1:10000

相关搜索:eNOS/NOS3抗体eNOS抗体NOS3单抗Anti-eNOS/NOS3 Antibody (Clone#6H2)
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